Use FWs or PS to design your layout. Slice your images and export them individually into a defined DW site.
You can use those images as part of your layout in DW. Either with a table layout - but you should consider using CSS to style your page.
Here are some beginner CSS tutorials by Adrian Senior - easy to understand and will get you up to speed in understanding basic CSS and then progress to more complicated layouts using CSS (I'm assuming you use DW).
http://www.macromedia.com/devnet/dre..._concepts.html
I would never let a graphics program write the html for my page. You will get a fixed (read rigid) layout, full of bloated code that will be impossible to troubleshoot if you don't know html. That's another thing, make sure you learn html.
www.w3schools.com
Nadia